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Umetrics simca-p+ software (version 14.0)
Simca P+ Software (Version 14.0), supplied by Umetrics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/simca-p++software+(version+14%2E0)/simca+software/pm40515704-84-6-10
Average 90 stars, based on 1 article reviews
simca-p+ software (version 14.0) - by Bioz Stars, 2026-09
90/100 stars

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Nuclear Magnetic Resonance:

Article Title: Ceramide subclasses identified as novel lipid biomarker elevated in women with polycystic ovary syndrome: a pilot study employing shotgun lipidomics.
Article Snippet: This study aimed to identify potential lipid biomarkers in women with polycystic ovary syndrome (PCOS) and determine their predictive value for PCOS.. Eighteen women with PCOS and 17 healthy controls were enrolled.. A multi-dimensional mass spectrometry-based shotgun lipidomics approach was employed to analyze serum lipid profiles.

Article Title: Metabolomics Analysis of Sporulation-Associated Metabolites of Metarhizium anisopliae Based on Gas Chromatography-Mass Spectrometry.
Article Snippet: Fungi 2023, 9, 1011 5 of 16 SIMCA-P software (version 14.0, Umetrics, Umea, Sweden) for multivariate statistical analysis.

Article Title: Maternal exposure to ambient PM 2.5 perturbs the metabolic homeostasis of maternal serum and placenta in mice.
Article Snippet: Epidemiological and animal studies have shown that maternal fine particulate matters (PM2.5) exposure correlates with various adverse pregnancy outcomes such as low birth weight (LBW) of offspring.. However, the underlying biological mechanisms have not been fully understood.. In this study, female C57Bl/6 J mice were exposed to filtered air (FA) or concentrated ambient PM2.5 (CAP) during pregestational and gestational periods, and metabolomics was performed to analyze the metabolic features in maternal serum and placenta by liquid chromatography-mass spectrometry (LC-MS).

Article Title: Effect of dietary taurine supplementation on metabolome variation in plasma of Nile tilapia.
Article Snippet: The NMR data were analyzed by SIMCA-P software (version 14.0, Umetrics AB, Umeå, Sweden) for multivariate statistical methods including principal component analysis (PCA), partial least squaresdiscriminant analysis (PLS-DA) and orthogonal partial least squares discriminant analysis (OPLS-DA).

Article Title: Paeoniae Radix Rubra can enhance fatty acid β-oxidation and alleviate gut microbiota disorder in α-naphthyl isothiocyanate induced cholestatic model rats
Article Snippet: Principal component analysis (PCA), partial least squares-discriminate analysis (PLS-DA), and hierarchical cluster analysis were employed to compare the metabolite profiles of different groups by using SIMCA-P software (version 14.0, Umetrics Umea, Sweden) and GraphPad Prism 8.3 (GraphPad Software, Inc., San Diego, CA, United States).

Article Title: Metabolomic analysis of HUVEC after Thermal denaturation UHPLC-MS/MS-based metabolomics.
Article Snippet: 1Department of Burns and Plastic Surgery, Xiangya Hospital, Central South University, Changsha, Hunan 410008, P. R. China; 2Department of Pathophysiology, Xiangya School of Medicine, Central South University, Changsha, Hunan 410008, P. R. China *Address correspondence to M.H. (email hmt1987123@126.com) Author Contributions: Fangqin Wu (Conceptualization, Writing—original draft, Writing—review & editing [lead]), Zhuoxian Yan (Data curation [equal], Formal analysis [lead]), Yanqin Ran (Funding acquisition, Investigation [equal]), Mengna Wang (Methodology, Project administration [equal]), Sifan Yang (Project administration, Resources [equal]), Situo Zhou (Resources, Software [equal]), Bimei Jiang (Validation [equal]), Pihong Zhang (Validation [equal]), Pengfei Liang (Visualization [lead]), and Mitao Huang (Software, Writing—review & editing [supporting]) Funding: Pengfei Liang is currently receiving a grant (2023JJ30909) from the Hunan Provincial Natural Science Foundation.. Situo Zhou is currently receiving a grant (82102325) from the China National Natural Science Foundation.. Mitao Huang is currently receiving a grant (2022JJ40791) from the Hunan Provincial Natural Science Foundation.

Article Title: Studies on the Changes of Fermentation Metabolites and the Protective Effect of Fermented Edible Grass on Stress Injury Induced by Acetaminophen in HepG2 Cells
Article Snippet: SIMCA-P software (Version 14.0, Umetrics, Umea, Sweden) was used to normalize the metabolite data.

Article Title: UPLC/Q-TOF-MS/MS-based metabolomics revealed the lipid-lowering effect of Ilicis Rotundae Cortex on high-fat diet induced hyperlipidemia rats.
Article Snippet: Ethnopharmacological relevance: Ilicis Rotundae Cortex (IRC), a Chinese crude drug, has been widely utilized in Guangdong and Guangxi provinces of China to treat or prevent cardiovascular diseases.. Aim of study: This investigation aims to study the lipid-lowering effect of IRC, as well as the regulating effect on the endogenous metabolites in hyperlipidemia rats.. Materials and methods: High-fat diet induced hyperlipidemia rats were administrated with different doses of IRC extract (0.5, 1.0 and 2.0 g/kg/day) for 5 weeks.

Software:

Article Title: Ceramide subclasses identified as novel lipid biomarker elevated in women with polycystic ovary syndrome: a pilot study employing shotgun lipidomics.
Article Snippet: This study aimed to identify potential lipid biomarkers in women with polycystic ovary syndrome (PCOS) and determine their predictive value for PCOS.. Eighteen women with PCOS and 17 healthy controls were enrolled.. A multi-dimensional mass spectrometry-based shotgun lipidomics approach was employed to analyze serum lipid profiles.

Article Title: Metabolomics Analysis of Sporulation-Associated Metabolites of Metarhizium anisopliae Based on Gas Chromatography-Mass Spectrometry.
Article Snippet: Fungi 2023, 9, 1011 5 of 16 SIMCA-P software (version 14.0, Umetrics, Umea, Sweden) for multivariate statistical analysis.

Article Title: Maternal exposure to ambient PM 2.5 perturbs the metabolic homeostasis of maternal serum and placenta in mice.
Article Snippet: Epidemiological and animal studies have shown that maternal fine particulate matters (PM2.5) exposure correlates with various adverse pregnancy outcomes such as low birth weight (LBW) of offspring.. However, the underlying biological mechanisms have not been fully understood.. In this study, female C57Bl/6 J mice were exposed to filtered air (FA) or concentrated ambient PM2.5 (CAP) during pregestational and gestational periods, and metabolomics was performed to analyze the metabolic features in maternal serum and placenta by liquid chromatography-mass spectrometry (LC-MS).

Article Title: Effect of dietary taurine supplementation on metabolome variation in plasma of Nile tilapia.
Article Snippet: The NMR data were analyzed by SIMCA-P software (version 14.0, Umetrics AB, Umeå, Sweden) for multivariate statistical methods including principal component analysis (PCA), partial least squaresdiscriminant analysis (PLS-DA) and orthogonal partial least squares discriminant analysis (OPLS-DA).

Article Title: Paeoniae Radix Rubra can enhance fatty acid β-oxidation and alleviate gut microbiota disorder in α-naphthyl isothiocyanate induced cholestatic model rats
Article Snippet: Principal component analysis (PCA), partial least squares-discriminate analysis (PLS-DA), and hierarchical cluster analysis were employed to compare the metabolite profiles of different groups by using SIMCA-P software (version 14.0, Umetrics Umea, Sweden) and GraphPad Prism 8.3 (GraphPad Software, Inc., San Diego, CA, United States).

Article Title: Metabolomic analysis of HUVEC after Thermal denaturation UHPLC-MS/MS-based metabolomics.
Article Snippet: 1Department of Burns and Plastic Surgery, Xiangya Hospital, Central South University, Changsha, Hunan 410008, P. R. China; 2Department of Pathophysiology, Xiangya School of Medicine, Central South University, Changsha, Hunan 410008, P. R. China *Address correspondence to M.H. (email hmt1987123@126.com) Author Contributions: Fangqin Wu (Conceptualization, Writing—original draft, Writing—review & editing [lead]), Zhuoxian Yan (Data curation [equal], Formal analysis [lead]), Yanqin Ran (Funding acquisition, Investigation [equal]), Mengna Wang (Methodology, Project administration [equal]), Sifan Yang (Project administration, Resources [equal]), Situo Zhou (Resources, Software [equal]), Bimei Jiang (Validation [equal]), Pihong Zhang (Validation [equal]), Pengfei Liang (Visualization [lead]), and Mitao Huang (Software, Writing—review & editing [supporting]) Funding: Pengfei Liang is currently receiving a grant (2023JJ30909) from the Hunan Provincial Natural Science Foundation.. Situo Zhou is currently receiving a grant (82102325) from the China National Natural Science Foundation.. Mitao Huang is currently receiving a grant (2022JJ40791) from the Hunan Provincial Natural Science Foundation.

Article Title: Studies on the Changes of Fermentation Metabolites and the Protective Effect of Fermented Edible Grass on Stress Injury Induced by Acetaminophen in HepG2 Cells
Article Snippet: SIMCA-P software (Version 14.0, Umetrics, Umea, Sweden) was used to normalize the metabolite data.

Article Title: UPLC/Q-TOF-MS/MS-based metabolomics revealed the lipid-lowering effect of Ilicis Rotundae Cortex on high-fat diet induced hyperlipidemia rats.
Article Snippet: Ethnopharmacological relevance: Ilicis Rotundae Cortex (IRC), a Chinese crude drug, has been widely utilized in Guangdong and Guangxi provinces of China to treat or prevent cardiovascular diseases.. Aim of study: This investigation aims to study the lipid-lowering effect of IRC, as well as the regulating effect on the endogenous metabolites in hyperlipidemia rats.. Materials and methods: High-fat diet induced hyperlipidemia rats were administrated with different doses of IRC extract (0.5, 1.0 and 2.0 g/kg/day) for 5 weeks.

Liquid Chromatography with Mass Spectroscopy:

Article Title: Ceramide subclasses identified as novel lipid biomarker elevated in women with polycystic ovary syndrome: a pilot study employing shotgun lipidomics.
Article Snippet: This study aimed to identify potential lipid biomarkers in women with polycystic ovary syndrome (PCOS) and determine their predictive value for PCOS.. Eighteen women with PCOS and 17 healthy controls were enrolled.. A multi-dimensional mass spectrometry-based shotgun lipidomics approach was employed to analyze serum lipid profiles.

Article Title: Metabolomics Analysis of Sporulation-Associated Metabolites of Metarhizium anisopliae Based on Gas Chromatography-Mass Spectrometry.
Article Snippet: Fungi 2023, 9, 1011 5 of 16 SIMCA-P software (version 14.0, Umetrics, Umea, Sweden) for multivariate statistical analysis.

Article Title: Maternal exposure to ambient PM 2.5 perturbs the metabolic homeostasis of maternal serum and placenta in mice.
Article Snippet: Epidemiological and animal studies have shown that maternal fine particulate matters (PM2.5) exposure correlates with various adverse pregnancy outcomes such as low birth weight (LBW) of offspring.. However, the underlying biological mechanisms have not been fully understood.. In this study, female C57Bl/6 J mice were exposed to filtered air (FA) or concentrated ambient PM2.5 (CAP) during pregestational and gestational periods, and metabolomics was performed to analyze the metabolic features in maternal serum and placenta by liquid chromatography-mass spectrometry (LC-MS).

Article Title: Effect of dietary taurine supplementation on metabolome variation in plasma of Nile tilapia.
Article Snippet: The NMR data were analyzed by SIMCA-P software (version 14.0, Umetrics AB, Umeå, Sweden) for multivariate statistical methods including principal component analysis (PCA), partial least squaresdiscriminant analysis (PLS-DA) and orthogonal partial least squares discriminant analysis (OPLS-DA).

Article Title: Paeoniae Radix Rubra can enhance fatty acid β-oxidation and alleviate gut microbiota disorder in α-naphthyl isothiocyanate induced cholestatic model rats
Article Snippet: Principal component analysis (PCA), partial least squares-discriminate analysis (PLS-DA), and hierarchical cluster analysis were employed to compare the metabolite profiles of different groups by using SIMCA-P software (version 14.0, Umetrics Umea, Sweden) and GraphPad Prism 8.3 (GraphPad Software, Inc., San Diego, CA, United States).

Article Title: Metabolomic analysis of HUVEC after Thermal denaturation UHPLC-MS/MS-based metabolomics.
Article Snippet: 1Department of Burns and Plastic Surgery, Xiangya Hospital, Central South University, Changsha, Hunan 410008, P. R. China; 2Department of Pathophysiology, Xiangya School of Medicine, Central South University, Changsha, Hunan 410008, P. R. China *Address correspondence to M.H. (email hmt1987123@126.com) Author Contributions: Fangqin Wu (Conceptualization, Writing—original draft, Writing—review & editing [lead]), Zhuoxian Yan (Data curation [equal], Formal analysis [lead]), Yanqin Ran (Funding acquisition, Investigation [equal]), Mengna Wang (Methodology, Project administration [equal]), Sifan Yang (Project administration, Resources [equal]), Situo Zhou (Resources, Software [equal]), Bimei Jiang (Validation [equal]), Pihong Zhang (Validation [equal]), Pengfei Liang (Visualization [lead]), and Mitao Huang (Software, Writing—review & editing [supporting]) Funding: Pengfei Liang is currently receiving a grant (2023JJ30909) from the Hunan Provincial Natural Science Foundation.. Situo Zhou is currently receiving a grant (82102325) from the China National Natural Science Foundation.. Mitao Huang is currently receiving a grant (2022JJ40791) from the Hunan Provincial Natural Science Foundation.

Article Title: Studies on the Changes of Fermentation Metabolites and the Protective Effect of Fermented Edible Grass on Stress Injury Induced by Acetaminophen in HepG2 Cells
Article Snippet: SIMCA-P software (Version 14.0, Umetrics, Umea, Sweden) was used to normalize the metabolite data.

Article Title: UPLC/Q-TOF-MS/MS-based metabolomics revealed the lipid-lowering effect of Ilicis Rotundae Cortex on high-fat diet induced hyperlipidemia rats.
Article Snippet: Ethnopharmacological relevance: Ilicis Rotundae Cortex (IRC), a Chinese crude drug, has been widely utilized in Guangdong and Guangxi provinces of China to treat or prevent cardiovascular diseases.. Aim of study: This investigation aims to study the lipid-lowering effect of IRC, as well as the regulating effect on the endogenous metabolites in hyperlipidemia rats.. Materials and methods: High-fat diet induced hyperlipidemia rats were administrated with different doses of IRC extract (0.5, 1.0 and 2.0 g/kg/day) for 5 weeks.



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